Nature, according to the critic Raymond Williams, is quite possibly “the most difficult word in the English language.” The genealogy of nature’s complexities—semantic, philological, epistemological, ontological—were the subject of this two-day conference that brought into dialogue historians of science, philosophy, art, and literature. How did early writers and artists and other thinkers know and encounter nature? What practices made nature legible? What ethics were thought to arise out of the environment? By what metaphors and strategies did pre-modern people represent the sensible world of matter? This event considered a wide variety of cultural productions in the medieval and early modern periods, seeking to have rethought the relation between fields of knowledge and to bridge the widening gap between the humanities and the sciences in our own universities.